This fact sheet looks at the history, funding, and future outlook of the President’s Emergency Plan for AIDS Relief (PEPFAR), the U.S. government’s major global initiative to combat HIV/AIDS.

The potential for the COVID-19 pandemic to significantly affect the health and development of low- and middle-income countries (LMICs), particularly those in sub-Saharan Africa, has serious implications for PEPFAR, the President’s Emergency Plan for AIDS Relief (PEPFAR). This issue brief examines the steps PEPFAR has taken to respond to the outbreak and the issues at stake.

This fact sheet provides a snapshot of global malaria efforts and examines the U.S. government’s role in addressing malaria worldwide, including current programs, funding, and key issues.

The U.S. government is the largest donor to global health in the world. This fact sheet breaks down the U.S. global health budget by program area: HIV/PEPFAR; tuberculosis (TB); malaria/the President’s Malaria Initiative (PMI); the Global Fund to Fight AIDS, Tuberculosis, and Malaria; maternal & child health (MCH); nutrition; family planning & reproductive health (FP/RH); global health security; and neglected tropical diseases (NTDs).

Jennifer Kates, Senior Vice President and Director of KFF’s Global Health & HIV Policy program, testified before the U.S. House of Representatives’ Committee on Foreign Affairs as part of a hearing on Unique Challenges Women Face in Global Health. Her testimony describes the role of the U.S. government in women’s global health and highlights challenges and opportunities to strengthen these efforts.

This updated fact sheet provides the latest data on the global HIV/AIDS epidemic, including impact by region, treatment and prevention efforts, and an overview of the U.S. and global responses to the epidemic.

This fact sheet describes the functions, governance, funding, and approach of the Millennium Challenge Corporation (MCC), with a particular focus on MCC’s engagement in global health.

This fact sheet provides an updated overview of federal funding for HIV/AIDS, highlighting key domestic and global HIV/AIDS programs and comparisons over time.

With ongoing questions about future U.S. support for multilateral health efforts as well as important markers on the near horizon, including donor replenishment conferences for both the Global Fund and Gavi within the next two years, this brief highlights five key facts about U.S. engagement with multilateral global health organizations.