Second Person With HIV Appears To Be In Remission Following Bone Marrow Stem Cell Transplant From Person Genetically Resistant To Virus
New York Times: HIV Is Reported Cured in a Second Patient, a Milestone in the Global AIDS Epidemic
“For just the second time since the global epidemic began, a patient appears to have been cured of infection with HIV, the virus that causes AIDS. The news comes nearly 12 years to the day after the first patient known to be cured, a feat that researchers have long tried, and failed, to duplicate. The surprise success now confirms that a cure for HIV infection is possible, if difficult, researchers said…” (Mandavilli, 3/4).
STAT: Ten years after the ‘Berlin patient,’ doctors announce a second person has been effectively ‘cured’ of HIV
“For the second time, doctors appear to have put HIV into ‘sustained remission’ with a stem cell transplant — effectively curing the recipient. Their work, which was published in Nature and will be presented at the annual Conference on Retroviruses and Opportunistic Infections in Seattle on Tuesday, may encourage scientists working on new gene therapies based on similar principles and give hope to those living with the infection…” (Sheridan, 3/4).
Wall Street Journal: Second HIV Patient May Be Cured After Stem-Cell Transplant
“…Nearly three years after the man received a stem-cell transplant from a donor who was genetically resistant to HIV, extensive testing shows he has no detectable amounts of the virus, according to the research, published in the journal Nature. He has been off antiretroviral drugs for about 18 months. Those drugs keep HIV, the virus that causes AIDS, in check. ‘He’s doing well,’ said Ravindra Gupta, HIV researcher at University College London who led the study…” (McKay, 3/4).
Washington Post: A decade after the first person was cured of HIV, a second patient is in long-term remission
“…The anonymous case, referred to as the ‘London patient’ by researchers, was cautiously reported … as still too ‘premature’ to be declared a cure … The advance was hailed by infectious disease specialists and even President Trump as a major advance, who called it ‘such great news for so many’ on Twitter. But physicians cautioned that while the new case should inject new energy and funding into efforts to develop treatments that use lessons from the two cases to put the disease in long-term remission, such stem cell transplants — which are not readily available and carry severe side effects in comparison to standard HIV treatments — would not become the standard of care for people infected with the virus…” (Johnson, 3/5).
Additional coverage of the “London patient” is available from Agence France-Presse, Al Jazeera, Associated Press, CNN, Deutsche Welle, The Economist, Fox News, The Guardian, The Hill, Nature, Reuters, Science, The Telegraph, TIME, and Vox.