NIH Begins Large Clinical Trial To Assess Preventive Care For People At High Risk Of Developing MDR-TB

National Institutes of Health: NIH launches large TB prevention trial for people exposed to multidrug-resistant TB
“A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis (MDR-TB) has begun. The study is comparing the safety and efficacy of a new MDR-TB drug, delamanid, with the decades-old TB drug isoniazid for preventing active MDR-TB disease in children, adolescents, and adults at high risk who are exposed to adult household members with MDR-TB. … ‘It is important to perform randomized, controlled clinical trials on how best to provide preventive care for people who come in close contact with individuals with MDR-TB, since this is a major gap in global public health policy,’ said Anthony S. Fauci, M.D. … The PHOENIx MDR-TB study will take place at more than 27 sites in at least 12 countries, including Botswana, Brazil, Haiti, India, Kenya, Peru, the Philippines, South Africa, Tanzania, Thailand, Uganda, and Zimbabwe…” (6/25).

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