PSI’s “Healthy Lives” blog reviews a recent Science magazine article written by James Shelton of USAID’s Bureau of Global Health in which he raises concerns about the use of antiretroviral drugs (ARVs) as a prevention strategy. The blog notes he especially expresses concerns over drug adherence and resistance. “Dr. Shelton does not entirely dismiss the usefulness of ARVs, but seeks to look a bit more critically at how effective they are as a prevention tool,” the blog states, noting that Shelton’s article concludes, “ARVs are no ‘magic bullet.’ But ARVs’ best potential is to contribute to the existing combination arsenal, which, well applied, can have a major impact in stemming the global HIV pandemic” (1/6).