The human papillomavirus (HPV) vaccine is the first and only vaccination that helps protect individuals from getting several cancers that are associated with different HPV strains. The vaccine holds the promise to safely prevent many kinds of cancers attributable to HPV that have long been responsible for the deaths of women and men. Since its introduction to the U.S. in 2006, the vaccine covers more strains of HPV, the dosage has dropped from three to two shots and the cost is fully covered by private insurance and public programs. The vaccine was originally recommended only for girls and young women, but was subsequently broadened to include boys, young men, and people of all genders. Uptake in the vaccine has risen over time, though there have been notable declines in vaccination rates since the COVID-19 pandemic. This factsheet discusses HPV and related cancers, use of the HPV vaccines for both females and males, and insurance coverage and access to the vaccine.

HPV and Cancer

HPV is the most common STI in the U.S. and is often acquired soon after initiating sexual activity. Approximately 42.5 million Americans are infected with HPV and there are at least 13 million new infections annually. There are more than 200 known strains of HPV, and while most cases of HPV infection usually resolve on their own, persistent infection with high-risk strains can cause cancer. HPV-related cancers have increased significantly in the past decade—between 2018 and 2022, over 49,000 people in the United States developed an HPV-related cancer compared to 30,000 in 1999. While HPV-related cervical and vaginal cancer rates have decreased since 1999, rates for oropharyngeal and anal HPV-related cancers have increased. 

Cervical Cancer

Over 90% of cervical cancer cases are HPV related, with two strains (16 and 18) responsible for approximately 66% of cervical cancer cases worldwide. In the U.S., it is estimated that 13,360 new cervical cancer cases were diagnosed in 2025. While cervical cancer is usually treatable, especially when detected early, approximately 4,320 deaths from cervical cancer occurred in 2025.

Despite widespread availability of cervical cancer screening, racial disparities in cervical cancer incidence and mortality rates persist in the U.S. For example, although Hispanic women have the second highest incidence rate of cervical cancer, cervical cancer mortality rates among this population are comparable to the national mortality rate. Black women, on the other hand, have the third highest incidence rate of cervical cancer, yet have the highest mortality rates of the disease (Figure 1). Another notable paradox is that Black and Hispanic women have the highest rates of recent Pap testing but higher rates of mortality attributable to cervical cancer. Lower rates in follow-up treatment after an abnormal screening result, differences in treatment options, diagnosis at later stages of disease progression, and negative experiences in the medical system may account for some of the disproportionate impact of cervical cancer.

Oropharyngeal and Anal Cancers

Approximately 22,585 cases of oropharyngeal (throat) cancer occur annually in the U.S, most of which (70%) are probably caused by HPV. Oropharyngeal cancers are the most common HPV-associated cancer among men and are more common among men than women (Figure 2). However, anyone who heavily uses both tobacco and alcohol is at much higher risk of developing these cancers. Research suggests that HPV vaccines can help protect against throat cancer since many are associated with HPV 16 and 18, two of the strains that the vaccine protects against. HPV is also responsible for the majority (91%) of the estimated 7,600 annual cases of anal cancer in the U.S. While cases of anal cancer are higher among women, men who have sex with men are at higher risk of developing anal cancer linked to HPV 16 and 18. Additional risk factors for anal cancer include a history of cervical cancer and having a suppressed immune system. Like oropharyngeal cancer, there has been an increase in the rate of anal cancers in the past 15 years.

HPV Vaccine Recommendations

Since 2016, Gardasil®9 has been the only HPV vaccine available in the U.S. The FDA approved first-generation Gardasil®—produced by Merck—in 2006, which prevented infection of four strains of HPV: 6, 11, 16, 18. In December 2014, Gardasil®9 was approved for use in individuals ages nine to 45 years old. This vaccine protects against the 9 strains of HPV associated with most cervical cancer, anal cancer, and throat cancer cases as well as most genital warts cases and some other HPV-associated ano-genital diseases. The vaccine was initially approved for cervical cancer prevention, but in 2020 the FDA broadened its approval to include the prevention of oropharyngeal cancer and other head and neck cancers. Current global research suggests Gardasil®9 protection is long-lasting: more than 10 years of follow-up data in both boys and girls indicate the vaccines are still effective and there is no evidence of waning protection, although it is still unknown if recipients will need a booster in the future. Other HPV vaccines show similar effectiveness. In Scotland, recipients of the bivalent HPV vaccine Cervarix®—which protects against HPV 16 and 18—who became fully vaccinated against HPV at age 12 or 13 have had no cases of cervical cancer since the vaccine program started in 2008. Additionally, new data from the American Society of Clinical Oncology shows that the vaccine reduced the risk of all HPV-associated cancers—including oropharyngeal, head, and neck cancers—by 50% in men. 

The federal Advisory Committee on Immunization Practices (ACIP) is responsible for issuing immunization recommendations for the U.S. population. ACIP is convened by the CDC and has historically been comprised of clinicians, scientists, public health experts, and other professionals with expertise in vaccine-related policies. In June 2024, during the Biden administration, the ACIP recommended that most adolescents receive a two-dose series of the HPV vaccine (Table 1). This recommendation was designed to promote immunization when the vaccine is most effective—before the initiation of sexual activity. Those already infected with HPV can also benefit from the vaccine because it can prevent infection against HPV strains they may not have contracted, but the vaccine does not treat existing HPV infections.

After the second Trump Administration took office, the Department of Health and Human Services (HHS) made changes in vaccine policy more broadly that also affected the HPV vaccine recommendations. In June 2025, Secretary of HHS, Robert F. Kennedy Jr., dismissed the entire membership of the ACIP and replaced them with new advisers, many of whom are known to be skeptical of vaccines. In December 2025, the newly reconstituted ACIP changed the recommendation from two doses to a single dose for adolescents. This recommendation, along with the other pediatric vaccine recommendation revisions made by the newly appointed committee, were blocked for the time being by a federal court in a legal challenge brought on by public health and health professional organizations led by the American Academy of Pediatrics. The ruling also blocked the changes that HHS made to the ACIP membership. As a result, the 2024 recommendations are currently in effect, for now.

While the FDA expanded its approval of the HPV vaccine to include adults ages 27 to 45, ACIP has not recommended routine catch-up vaccinations for all adults in this age group. ACIP recommends that adults ages 27 to 45 who have not been properly vaccinated and who may be at risk for new HPV infections consult with a medical professional about receiving the vaccine. 

Uptake

In 2024, over 60% of adolescents aged 13-17 in the U.S. were up-to-date with their HPV vaccinations (HPV UTD). On average, adolescents who were Asian, Black, or covered by Medicaid were more likely to be HPV UTD compared to adolescents who were White, privately insured, or uninsured. HPV vaccination rates among teen boys are slightly lower than for girls (61% vs. 64% HPV UTD in 2024), but they have been rising since 2016.

HPV vaccination rates vary by state, ranging from a low of 39% of adolescents being HPV UTD in Mississippi to a high of 80% in Massachusetts (Figure 3). Some states, such as Hawaii, Rhode Island, Virginia, and D.C., have laws that require HPV vaccination for school entry. In California, the Cancer Prevention Act requires schools to notify families of 6^th grade children about HPV vaccine recommendations and advise them to follow guidelines but does not require them to adhere to them for school entry. Vaccine exemptions due to religious or personal beliefs are permitted in most states.

Some people begin the vaccine series but do not complete it. In 2024, 79% of adolescent girls and 77% of boys received at least one dose of the HPV vaccine. Recent trends in vaccination coverage show that overall HPV vaccination initiation has stalled for the third consecutive year, and throughout the last decade, rates continue to remain lower among adolescents who live in predominately rural areas compared to those in urban areas. The findings indicate that children were more likely to be vaccinated when their parent/guardian received a vaccine recommendation for their child from a healthcare provider. In addition, while vaccine initiation among adolescents overall remained steady, initiation rates in recent years have slightly declined among adolescents who were uninsured or covered by Medicaid (Figure 4).

Vaccine hesitancy may also contribute to lower HPV vaccination coverage among these subgroups. Prior to the pandemic, parents’ top reasons for not vaccinating their children were perceptions of safety concerns and the belief that the vaccine was not needed. Since the pandemic began, some providers have observed an increase in vaccine hesitancy or refusal in parents of adolescents they attribute to difficulties cased by COVID-19 or mistrust in vaccines. HHS Secretary Kennedy also has a history of vaccine skepticism, and his views along with the vacillating recommendations for the HPV vaccine over the course of the second Trump administration will likely add to the hesitancy and confusion among parents and clinicians.

Vaccine Financing

There are multiple sources of private and public financing that assure that nearly all children and young adults in the U.S. have coverage for the HPV vaccine. Many of the financing entities base their coverage on ACIP recommendations.

The Affordable Care Act (ACA) requires public and private insurance plans to cover a range of recommended preventive services and ACIP recommended immunizations without consumer cost-sharing. Plans must cover the full charge for the HPV vaccine, as well as pap tests and HPV testing for women. 

Public Financing 

Vaccines for Children — Through the VFC program, the CDC purchases vaccines at a discounted rate and distributes them to participating healthcare providers. All children are eligible through age 18 if they are uninsured, underinsured, Medicaid-eligible, Medicaid-enrolled, or American Indian or Alaska Native.  

Medicaid — Medicaid covers ACIP-recommended vaccines for enrolled individuals under age 21 through the Early and Periodic Screening Diagnosis and Treatment program (EPSDT). Adults 21 and older who are insured through Medicaid are covered for approved adult ACIP-recommended vaccinations without cost-sharing.  

Public Health Service Act — Section 317 of the Public Health Service Act provides grants to states and local agencies to help extend the availability of vaccines to uninsured adults in the United States. These are often directed towards meeting the needs of priority populations, such as underinsured children and uninsured adults.  

Merck Vaccine Patient Assistance Program — Merck, the manufacturer of Gardasil®9 has established assistance programs to provide free HPV vaccines in the United States. To qualify, individuals must be aged 19 or older, uninsured, and low-income.  

Children’s Health Insurance Program (CHIP) — Children who qualify for CHIP are part of families whose incomes are too high to qualify for Medicaid but too low to afford private insurance. Each state has its own set of specific qualifications for CHIP. The program is managed by the states and is jointly funded by the states and the federal government. CHIP programs that are separate from the Medicaid Expansion must cover ACIP-recommended vaccines for beneficiaries since they are not eligible for coverage under the federal VFC. 

Measles has been officially “eliminated” from the U.S. since 2000, which means the country had not seen very large outbreaks and had not had 12 months or more of uncontrolled domestic transmission of the virus since before that time. However, a series of measles outbreaks began in the U.S. in early 2025 that continue today: from January 2025 through the end of March 2026, U.S. states have reported over 3,800 measles cases. Several factors have contributed to the ongoing transmission of measles in the U.S. These include funding and staffing cuts for public health efforts at the federal, state, and local levels that have affected measles prevention and response efforts across the country, along with mixed messages from federal health officials such as Department of Health and Human Services (HHS) Secretary Robert F. Kennedy, Jr. regarding measles response at the same time there has been no Senate-confirmed leader at CDC for almost the whole period since these outbreaks began. Further, there is increased skepticism among the public about the safety and effectiveness of measles vaccines and a decline in trust of health authorities in general, which has contributed to lower measles vaccination rates and complicated outreach and communication efforts in addressing the current outbreak.

What does this mean for U.S. elimination status and control of the disease going forward? This policy watch provides an overview of the definition of measles elimination, including how this status is decided and declared, and its significance. Further, it assesses how the current measles outbreak may threaten elimination status and what that might mean for control of measles in the U.S.

Measles and the Measles Vaccine

Measles is one of the most contagious human viruses. When spreading in a population with no prior immunity, it is estimated that on average one measles case can result in 12- 18 other cases (this is the basic “reproduction number” of measles). While most measles infections are not severe, health complications can occur in about 30% of measles cases, and around 1 in 1,000 measles infections lead to death. There is a higher risk of severe outcomes in young children and immunocompromised individuals. Among the 1,309 confirmed measles cases so far in 2025, 164 (13%) were hospitalized and three deaths have occurred. Besides the risk of the infection itself, measles can also have long-lasting negative impacts on the immune system more broadly, especially in children, leaving people more prone to serious outcomes from other infections. Those who recover from a measles infection usually develop long-term immunity to further measles infection.

Measles vaccines have been available in the U.S. since 1963 and are safe and effective at providing protection against illness and, importantly, against infection and onward transmission of the virus. It is estimated that two doses of a measles-containing vaccine are 97% effective in preventing infection. CDC recommends children get their first measles vaccine dose between 12 and 15 months of age, and the second dose between 4 and 6 years of age, before entering school. Currently, the most common measles-containing vaccine in the U.S. is the combination measles, mumps and rubella (MMR) vaccine. Epidemiologists estimate that when >95% of a population has immunity to measles, through previous infection or vaccination, then “herd immunity” is reached and measles transmission is interrupted and large outbreaks will not occur. Therefore, at least 95% coverage with two doses of the measles vaccine is a common goal for immunization campaigns and is the current Healthy People 2030 target in the U.S. However, it is estimated that national two-dose MMR coverage in the United States is for children entering kindergarten in 2024 was 92.5%, a figure that had declined from 94.7% in 2011. In addition, this coverage varied significantly across states, ranging from 78.5% in Idaho to 98.2% in Connecticut. Just 10 states had reported coverage levels at 95% or above in 2024-2025.

National, Regional, and Global Measles Elimination Goals and Prior U.S. Certifications

The first national goal to interrupt measles transmission in the U.S. was announced in 1966, just a few years after licensure of the first measles vaccine, and CDC announced further measles elimination goals in 1978 and 1993. In 1994, the member states of the Pan American Health Organization (PAHO, the Americas regional office of the World Health Organization (WHO) that includes the U.S.) set a goal of interrupting endemic measles virus transmission in the region by the year 2000 and in 2012, member states of the WHO endorsed a Global Vaccine Action Plan that included a measles elimination goal for all six WHO regions by 2020. 

Despite setting multiple goals since 1966, the U.S. did not officially achieve measles elimination status until 2000. Verification of elimination was carried out first through internal CDC and external expert review of U.S. strategy and programs to address measles, and epidemiological data on cases and vaccinations, which were compared against predetermined benchmarks for success. In March 2000, the National Immunization Program at CDC convened an external panel of experts to review the available data, and the panel concluded that criteria for elimination had been met, and officially stated that measles had eliminated from the U.S. Subsequently, a process was undertaken to re-verify U.S. elimination status in 2011, when the CDC’s National Center for Immunization and Respiratory Diseases assembled panel of external experts to review available evidence on U.S. measles programs and epidemiology since 2000. The panel agreed that measles elimination had been maintained, issuing a final report in March 2012. The U.S. has continued to review measles elimination status over time, including through an external expert committee known as the U.S. National Sustainability Committee for the Elimination of Measles, Rubella, and Congenital Rubella Syndrome.

Given the region-wide goal set in 1994, PAHO has also reviewed and verified national measles elimination for countries of the Americas, including the U.S. In 2007, PAHO member states created an international committee to verify country-level interruption of measles transmission and called for the creation of national-level commissions to help compile and submit related documentation to PAHO for review by an expert committee. Subsequently, PAHO’s Measles and Rubella Elimination Regional Monitoring and Re-Verification Commission (MRE-RVC) has met annually to review available evidence and issue reports on the status of elimination in PAHO member states with the U.S. consistently being designated as having sustained elimination. However, at its most recent meeting (in November 2025), the MRE-RVC placed the U.S. in the category of “sustained with major concerns.”

What Does it Mean to “Eliminate” Measles?

According to the guidelines developed by the U.S. and other PAHO member states, measles elimination has been defined at a basic level as: “Interruption of endemic measles virus transmission for a period greater than or equal to 12 months, in the presence of high-quality surveillance.” By contrast, measles is considered endemic in a given area if there is continuous transmission over a 12-month period.

In their review processes, CDC and external experts have used a variety of epidemiological and programmatic indicators, such as measles cases and transmission patterns, public health measures and response capabilities, and vaccination rates to help determine if endemic measles transmission has been “interrupted” and whether surveillance is “high-quality.” For example, when experts reviewed data for re-certification of measles elimination for the U.S. in 2011, the following primary lines of evidence were used (most covering the period 2001 to 2011) and the committee decided collectively that the data supported the conclusion that endemic measles virus transmission was interrupted in the presence of high-quality surveillance:

• There were fewer than one reported measles case per 10 million population;
• The great majority of measles cases were imported from areas outside the U.S. and most imported cases did not lead to further spread inside the U.S. – over the study period, 40% of cases were found to be imported;
• The number and size of measles outbreaks over that period were small: a total of 64 outbreaks (median 4 outbreaks/year), with a median outbreak size of 6 cases. Only 16 outbreaks included 10 or more cases;
• Measles vaccination rates among children had been sustained at high levels (>95%) over the study period, with no significant differences in coverage by race/ethnicity;
• Data from national surveys indicated that population immunity to measles was above the “herd immunity” threshold; almost all age groups had seropositivity rates for measles antibodies over >95%, and;
• Programmatic data on laboratory testing and case investigation performance indicated that U.S. surveillance adequately and quickly identified measles cases and transmission chains.

Prior to 2025, the largest outbreak of measles since U.S. elimination was declared occurred in 2018-2019. Imported measles cases in late 2018 had started a large outbreak centered in several close-knit communities with low vaccination rates in New York City and surrounding counties. As more measles cases came to be identified, state and local officials began to implement public health measures to combat the outbreak including declaring a public health emergency, mandating vaccinations and instituting fines for parents not vaccinating their children, which led to 60,000 MMR vaccine doses administered in affected areas in a few months. Authorities also closed schools where measles transmission occurred, prohibited unvaccinated children from attending school, and engaged in extensive communication and outreach efforts. At the time, federal agencies such as CDC provided technical assistance and other support and made clear statements about the importance of measles vaccinations, with then-CDC Director Robert Redfield stating “I encourage all Americans to adhere to CDC vaccine guidelines in order to protect themselves, their families, and their communities from measles” and pointing out that “organizations had been deliberately targeting these communities with inaccurate and misleading information about vaccines.” The White House also echoed this, with President Trump stating “vaccinations are so important” and encouraging parents to vaccinate their children against measles.  These combined efforts were effective in containing the New York outbreak in under 12 months, as transmission was interrupted by August 2019.

Does the Current Outbreak Threaten U.S. Measles Elimination Status?

In 2025, the U.S. had more reported measles cases, outbreaks, affected states, and deaths than in any year since 1992, and measles outbreaks have continued to occur in 2026. The pace of reported measles cases has fluctuated from early 2025 until March 2026, but there have been continual outbreaks and more states affected over that time period. A higher percentage of cases since 2025 have been due to local transmission vs. importation compared to prior years indicating local transmission has been the primary source of reported cases. Further, U.S. MMR vaccination rates have continued their steady decline and in many locations across the country levels of vaccination are below that needed for herd immunity. Table 1 summarizes key U.S. measles outbreak indicators as reported by CDC for 2025 and year-to-date (through March) 2026.

Compared to the elimination period of 2001 to 2011 discussed above, these metrics are notably worse. There were 64 measles outbreaks in total over ten years (2001 -2011) but in 2025 there were 48 outbreaks, and there have been 16 new outbreaks in 2026 through March. While 40% of measles cases were imported in the 2001-2011 period, in 2025 just 10% of cases were imported and just 6% in 2026 (meaning more local transmission chains). There was one measles death over ten years during the elimination period, while there three in 2025 (none have been reported in 2026 to date). Many of these 2025 and 2026 data points are also worse than those from 2019, when U.S. measles elimination status was last threatened. For example, from January to October 1, 2019 (by which time the large outbreaks centered in New York had been contained), there had been 1,249 total measles cases, and 22 total outbreaks across 17 states; 2025 far surpassed those numbers. 

Primary responsibility for public health responses to measles sits with state and local health departments. At the moment, metrics on state and local capacities and response times for measles are not available, so gauging whether U.S. surveillance remains “high-quality” is challenging. However, in 2025 and 2026, state and local public health departments have faced cuts in funding and support from the federal government compared to previous years, which may impact their ability to track and respond to measles outbreaks. In recent years, the federal government has provided over half of state and local health public health departments’ budgets. There is little evidence that states most affected by measles in 2025, such as Texas, New Mexico, and South Carolina, have taken the kinds of measures that New York officials implemented to contain outbreaks in 2019: vaccination mandates, school restrictions and fines. While federal agencies such as CDC have been providing technical assistance and funding to affected areas, HHS Secretary Robert F. Kennedy, Jr. has downplayed the risks of measles and has provided mixed messages about the importance of vaccination compared to alternative treatments for measles, and CDC has been without a permanent Director since late August 2025. In January 2026, then Deputy Director of CDC Ralph Abraham stated that the measles outbreaks experienced by the U.S. were “just the cost of doing business…we have these communities that choose to be unvaccinated. That’s their personal freedom.” More recently, acting CDC Director Jay Bhattacharya has made stronger statements of support for measles vaccinations, saying in March 2026 that “measles is preventable and vaccination remains the most effective way to protect yourself and those around you.”

Data also show that national measles vaccination levels declined over the past five years, with kindergarten and childhood measles coverage rates dipping well below the 95% goal. Measles vaccination rates for kindergarteners at the national level declined from 95.2% in 2019-2020 to 92.5% in 2024-2025 (the latest available data), and over three-quarters of states had MMR vaccination rates below the target rate of 95% in the latest data. Additional studies have found that 78% of U.S. counties reported a decline in two-dose measles vaccine coverage in children, with the average county-level measles vaccination rate falling from 93.9% in 2019 to 91.3% in 2024. In 2025, 8% of U.S. measles cases had history of MMR vaccination while 92% of cases were unvaccinated or had unknown vaccination status; in 2026 so far 93% of cases were in unvaccinated individuals. Lower MMR vaccination rates have occurred in the context of broad declines in people’s trust in health authorities and in vaccinations in general. For example, KFF polling has found that parents are frequently exposed to misinformation about measles and the MMR vaccine, and in 2025 almost 20% of adults report they believed the false claim that “getting the measles vaccine is more dangerous than become infected with measles” is probably or definitely true.

Therefore, if current trends hold through the rest of the year there would appear to be grounds for the U.S. to lose measles elimination status, using prior definitions and benchmarks.

U.S. Measles Outbreaks in a Regional and Global Context

The U.S. is not alone in facing higher numbers of measles cases since 2025. There have also been large outbreaks in Mexico (6,213 reported cases in 2025) and Canada (5,463 reported cases in 2025). In fact, in November 2025 PAHO declared that Canada no longer holds measles elimination status due to having over 12 months of continual measles transmission. Like in the U,S., these outbreaks have been concentrated in communities with low vaccination rates. According to PAHO, in the region of the Americas, a total of 14,975 cases of measles were reported in 2025 across 13 countries, with almost all of these cases coming from North America. WHO reports that through June of this year, there were a total of 276,240 measles cases globally with large outbreaks occurring in the European and Eastern Mediterranean regions, in addition to the Americas. Outside of North America, the countries with the highest numbers of measles cases between August 2025 and January 2026 were India (12,135 cases), Angola (11,941), and Indonesia (8,892). As indicated in a standing travel warning from CDC, more circulation of measles regionally and globally means a higher risk that U.S. residents traveling internationally can be exposed, which raises the risk of importing measles and sparking new domestic outbreaks.

Looking Ahead

The next steps in determining U.S. measles elimination status include an internal federal-led review of state and CDC epidemiological data. A key outstanding question is whether transmission over the past year derived from the outbreak that began in January 2025 in West Texas, or whether outbreaks have been due to unconnected importation events. If cases over the past year across different states are epidemiologically linked to those from the Texas outbreak it would indicate continual chains of transmission extending more than 12 months, jeopardizing measles elimination status. Using genetic testing of measles virus isolated from patients, scientists can determine transmission patterns. CDC is currently working with partners to perform such sequences and publish the findings. These, along with other data, will be reviewed by the external expert PAHO committee (the Measles, Rubella, and Congenital Rubella Syndrome Elimination Regional Verification Commission, MRE-RVC), which is responsible for a determination of U.S. elimination status. After initially announcing a review meeting would take place in April 2026, PAHO changed the date for the U.S. measles elimination review to November 2026, which coincides with the regularly scheduled annual MRE-RVC meeting.

The elimination of measles in the U.S. was a notable public health achievement made possible by sustained investments in prevention and response capacities, support of vaccination, and commitment to the goal of elimination. However, this status is currently at risk, as demonstrated by the many factors discussed above. Losing measles elimination status would signify that the same commitment to measles prevention and control may no longer be present in the U.S. It could signify a future where measles is endemic and continuously circulating, especially if vaccination rates continue to decline. That would bring more hospitalizations and more deaths, particularly among vulnerable children, from a very preventable disease. There could be broader implications for communities across the country, which may have to contend with more frequent decisions about whether and when to close day cares and schools in the face of transmission risks. The societal costs of measles outbreaks are high, so continuous outbreaks would place an additional burden on already weakened and depleted public health systems, and would raise questions about what the appropriate level of support and funding should be from the federal government for outbreak response at the state and local levels.

On April 3, 2026, the administration released its Fiscal Year 2027 budget request. The budget request includes discretionary funding for U.S. global health programs at the State Department, Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH). The proposed budget includes significant reductions in and restructuring of global health funding, including the elimination of some programs and activities as follows:

State:

• Global Health Programs (GHP) account: The main account that supports global health programs totals $5.1 billion in the request, $4.3 billion below the FY 2026 amount ($9.4 billion).
• Bilateral Funding:
  • Program areas: The FY27 request proposes to “eliminate disease-specific accounts and provide the Department crucial agility to address the actual needs of each recipient country—across HIV/AIDS and other infectious diseases such as Malaria, Tuberculosis, and Polio—to strengthen global health security and protect Americans from disease.”
  • Eliminated funding: Funding for family planning and reproductive health (FP/RH) is specifically eliminated in the FY27 request. The request does not mention funding for nutrition, the vulnerable children program, or neglected tropical diseases (NTDs), so it is possible funding for these programs is also eliminated.
• Multilateral Funding:
  • The Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund): Does not include a specific funding amount for the Global Fund in FY 2027 but commits to “leveraging $2 from other donors for every $1 from the United States.” It also states that funds may not exceed 33% of the total amount contributed to the Global Fund.
  • Gavi, the Vaccine Alliance (Gavi): Does not provide funding for Gavi and states that any future FY 2027 funding for Gavi is “contingent on the organization making necessary reforms and meeting certain benchmarks on vaccine safety.”
  • Eliminated funding: Eliminates funding for the Pan American Health Organization (PAHO), the United Nations Population Fund (UNFPA), and the World Health Organization. Funding for the United Nations Children’s Fund (UNICEF) was not specifically mentioned in the request. UNICEF and UNFPA have historically been provided through the International Organizations and Programs (IO&P) account, and the request states that “Authorities under IO&P were requested under the America First Opportunity Fund.”
• Policy Provisions:
  • Period of availability: Proposes “aligning all Global Health Program accounts into 3-year period of availability.” Historically, funding has been available for 5-years for HIV and 2-years for other disease areas.
  • Promoting Human Flourishing in Foreign Assistance (PHFFA): Includes language to apply the PHFFA policy to all applicable foreign assistance accounts, including the GHP account.

Centers for Disease Control and Prevention (CDC):

• CDC’s Global Health Center: Funding for CDC’s Global Health Center totals $663.8 million, and funding for all program areas remained level with FY 2026. This amount does not include funding for Parasitic Diseases & Malaria, which is proposed to be moved to another part of CDC, Emerging Infectious Diseases, without specifying an amount. FY 2027 global health funding at CDC is flat when Parasitic Diseases & Malaria funding is removed from the FY 2026 total.
• CDC’s role in global health: The request states that “CDC serves as the nation’s first line of defense against emerging infectious diseases, protecting American communities, U.S. businesses, and the broader economy. CDC will play a key role in implementing an America First approach to global health to replace the functions of the World Health Organization.”

National Institutes of Health (NIH):

• NIH funding: The FY 2027 request proposes reforms to the NIH, including overall funding decreases (while the NIH budget justification has not yet been released, the HHS Budget in Brief states that the overall decrease is approximately $5 billion). The budget does propose to eliminate funding for the Fogarty International Center (FIC), which was funded at $95 million in FY 2026.

See the table below for additional detail on global health funding. See other budget summaries (including the summary on FY 2026 Labor, Health and Human Services, Education, and Related Agencies [Labor HHS] and FY 2026 National Security, Department of State and Related Programs [NSRP] global health funding) and the KFF budget tracker for details on historical annual appropriations for global health programs.

Resources:

• White House budget resources
• State Department, FY 2027 International Affairs Budget
• Centers for Disease Control and Prevention, FY 2027 CDC Congressional Justification
• National Institutes of Health, HHS Budget in Brief Fiscal Year 2027

The 2025 reconciliation law requires states to condition Medicaid eligibility for adults in the Affordable Care Act (ACA) Medicaid expansion group and enrollees in partial expansion waiver programs (Georgia and Wisconsin) on meeting work requirements starting January 1, 2027. Implementing work requirements will require complex changes to eligibility and enrollment systems, as well as enrollee outreach and education, staff training, and coordination with managed care plans, providers, and other stakeholders. As states are preparing to implement work requirements and other changes in the reconciliation law, many states are facing more tenuous budget situations with slowing revenue growth and broader reductions in federal funding. 

The governor projects a $3 billion budget deficit for fiscal year (FY) 2027 and is proposing changes to slow Medicaid spending and close budget gaps while anticipating reductions in federal funding primarily due to changes included in the 2025 reconciliation law. Overall, state data show that California Medicaid (Medi-Cal) provides coverage to 14.8 million enrollees as of June 2025. Under the Governor’s proposed budget, Medicaid accounts for about 40% of the state budget and 20% of General Fund spending in FY 2027 or $49 billion (an increase from $45 billion in FY 2026). This issue brief examines the current budget context in California, the governor’s recently proposed budget, the state’s Medicaid Advisory Committee (MAC) meeting, state implementation plan documents and guidance, and data from KFF’s Medicaid work requirements tracker to provide initial insight into how California — the state with by far the largest number of Medicaid enrollees — is preparing to implement Medicaid work requirements during ongoing state budget debates.

What is the budgetary context as California prepares to implement work requirements?

California is facing a more tenuous fiscal climate like in other states, which led the state to implement spending cuts in FY 2026. In the past year, revenue volatility and rising costs have led to slowing state revenue growth following a period of record-breaking revenue and expenditure growth for states after the initial pandemic-induced economic downturn. Facing budget pressures in FY 2026 due to increasing spending demands from Medicaid, employee health care, education, housing, and disaster response, California implemented measures to slow cost growth in Medicaid, most of which may be attributed to higher utilization of services per-enrollee, higher service costs, and recent state benefit expansions. The changes in FY 2026 included partially restoring the asset test for seniors and persons with disabilities, ending Medicaid coverage of GLP-1s for obesity treatment, and ending supplemental payments for dental services.

In addition to Medicaid cuts, the state also implemented restrictions to their state-funded health program for immigrant adults who would qualify for Medicaid if not for their immigration status, including pausing enrollment and benefits, implementing cost-sharing, and reducing payments to health centers for services provided to undocumented immigrants. The state increased spending in other areas to fill in losses in federal funding, such as allocating funds to replace ACA Marketplace subsidies for some enrollees after the expiration of ACA enhanced premium tax credits at the end of 2025. California received $233 million this year from the federal Rural Health Transformation Program to help offset the 2025 reconciliation law impact on rural areas, though the program is unlikely to fully cover losses over time due to cuts in the law and from other federal policy changes.

The California governor’s proposed budget projects a $3 billion structural deficit for FY 2027 that is expected to grow to $22 billion in FY 2028 due to costs outpacing revenues and changes included in the 2025 reconciliation law. The governor’s proposed budget estimates that the 2025 reconciliation law would result in costs of $1.4 billion General Fund in FY 2027, with $1.1 billion in Medicaid alone. The proposed budget anticipates cost increases despite estimated reductions in spending due to eligibility changes that are expected to reduce the number of enrollees once they go into effect in 2027 (including work requirements, more frequent redeterminations, immigrant eligibility changes, and retroactive coverage). The budget also assumes cost increases (or revenue decreases) due to financing changes related to the state’s managed care tax and the hospital quality assurance fee, which are offset by modest revenue increases in the state’s managed care behavioral health tax. Other financing changes (including changes to state directed payments) will likely have larger impacts beyond the 2027 budget window.

In addition to the required federal Medicaid changes, the governor’s proposed budget voluntarily imposes Medicaid work requirements and six-month redeterminations on certain enrollees in California’s state-funded health program for immigrants. At the local level, voters in one California county approved a ballot measure in December 2025 to raise taxes to backfill Medicaid funding gaps caused by the 2025 reconciliation law, and voters in other counties may also consider similar ballot measures later in 2026.

What do we know about how California will implement work requirements?

Most Medicaid adults in California under age 65 who will be subject to the new work requirements are already working or attending school. As of June 2025, there were about five million expansion enrollees in California who could be affected by the new requirements. KFF analysis indicates that roughly 63% of Medicaid adults without dependent children in California who could be subject to work requirements work 80 or more hours per month or are attending school. In addition, many enrollees who are not working the required hours will likely qualify for exemptions from the new work requirements. California currently estimates that the introduction of work requirements will result in up to 1.4 million individuals being disenrolled over the reconciliation law implementation period.

In initial state guidance, California provided a first look into how the state is planning to implement work requirements. Current state guidance discusses policies such as look-back periods, data matching, enrollee verification, and short-term hardship exceptions (Table 1). The guidance also provides early plans for individuals experiencing changes in circumstances and transitioning into the ACA Medicaid expansion group from groups not subject to work requirements, saying they will be subject to work requirement verification at their next renewal rather than immediately at the time of transition. There remain several areas where the state is waiting on federal guidance before clarifying policies (e.g., definitions for the “medically frail” exemption, standards for self-attestation, acceptable forms of verification, and criteria for exemptions and work activities).

In a recent Medicaid Advisory Committee (MAC) meeting, California state officials also provided early insight into the state’s outreach and communication plan. All states are required to have a Medicaid Advisory Committee to advise the State Medicaid agency about health and medical care services. These groups include Medicaid enrollees, advocates, and providers. The new law requires states to begin outreach to notify individuals (by mail and at least one additional method) of the new requirements at least three months before the start of the first compliance “look-back” period and notify individuals “periodically thereafter.” The proposed Governor’s Budget includes $4 million for navigators to assist with eligibility, enrollment, and retention. In its March MAC meeting, the state outlined some key tenets of its outreach plan:

• Early outreach. California has already started outreach to members (e.g., text messages) and plans to continue to spread awareness by sharing flyers, social media posts, text messages, and relying on word of mouth through local partners.
• Training and toolkits. The state plans to share toolkits and train county eligibility workers, Department of Health Care Services (DHCS) Coverage Ambassadors, navigators, health plans, doctors’ offices, clinics, community health workers, and community-based partners.
• Maximizing reach. California will translate materials into 19 languages and work with “trusted messengers” (e.g., local groups) to help people get and retain coverage.
• Automation and simplification. The state will aim to use existing data, when possible, to minimize extra steps for individuals and to simplify forms and renewal instructions as much as possible.

KFF is tracking metrics related to Medicaid enrollment, renewal outcomes, and application processing times that can provide insight into California’s potential readiness to implement data matching and other necessary system changes. As of December 2025, nearly nine in 10 applications in California were processed within 30 days and nearly three in four individuals going through a Medicaid redetermination had their coverage renewed. Of people who retained coverage, 73% were renewed through ex parte processes (meaning the state verifies ongoing eligibility through available data sources before sending a renewal form or requesting documentation from an enrollee). Early data match estimates shared during the recent MAC meeting list around 1.8 million individuals able to be determined exempt or compliant via an automated source based on August 2025 enrollment data, although these estimates are likely to change as the state integrates additional data sources and implements cross-system information data sharing. In its implementation plan, California acknowledges that ex parte rates have dropped back to levels from before the unwinding of COVID-era guarantees of continuous Medicaid enrollment and anticipates the work requirements to increase the manual administrative workload to support members in retaining coverage. Among those who were disenrolled, 92% were terminated for procedural reasons (a higher rate than the national average of 78%). While these metrics provide insight into California’s Medicaid eligibility systems, they are not the only indicators or predictors of successful implementation of work requirements, which will also require enrollee outreach and education, staff training, and coordination with managed care plans, providers, and other stakeholders.

As states implement work requirements, ongoing monitoring can help assess how processes are working and identify areas of concern. Central to that oversight is timely data on renewal outcomes, including data on disenrollments related to work requirements. While available data (highlighted above) from CMS can be helpful, these data are not timely enough for real-time monitoring and they do not isolate outcomes for the expansion population. States can fill that gap by reporting more timely data on application and renewal outcomes that include breakouts for individuals subject to work requirements. In the MAC presentation slides, California state officials communicated their intention to monitor key metrics related to the impact of work requirement implementation, including the number of individuals subject to work requirements, the number of individuals in compliance with reporting requirements, and the number of individuals who lose coverage due to procedural disenrollments.

KFF has long examined the role of health care in U.S. elections, tracking how the issue ranks among voters’ top concerns, which political party or candidate voters’ trust, and how health care issues might motivate voter turnout. This issue brief summarizes the role health care has historically played in elections using KFF polls, exit polls, and other data to show how health care, especially the issue of health care costs, may play a role in the upcoming 2026 midterm elections.

Key Takeaways

• Historically, health care has often been among the most important issues to voters: In most presidential and midterm election year polling since 1992, health care ranked among voters’ top concerns, with “the economy” taking the top spot in most elections. While these polls usually ask voters to choose between health care and the economy as separate issues, KFF polling has long shown how health care costs are an important factor in people’s economic concerns. On its own, health care rose to the top spot in the 2018 midterm exit poll, immediately after the failed attempt to repeal and replace the Affordable Care Act (ACA). In almost all recent elections, Democratic voters have consistently been more likely than Republican voters to say that health care is a top electoral issue.
• Partisan advantages on health care and the economy: Historically, Democrats have held an advantage over Republicans on who voters trust to handle health care issues, while Republicans have usually been seen as stronger on the economy. Health care costs sit at the intersection of these issues, raising questions about which party voters will trust more to address the affordability of health care. Recent KFF polling data suggests that heading into the 2026 election, the Democratic Party has the advantage on health care costs, but notably, about a quarter of voters, rising to four in ten independent voters, say they trust neither party on this issue.
• Implications for the 2026 Midterms: Looking ahead to the 2026 midterm elections, the issue of health care affordability may help candidates motivate their bases. As of March 2026, Democrats maintain an advantage over Republicans in voter trust to address the cost of health care and prescription drugs, and majorities say health care costs are important to their vote. Who voters will ultimately trust to handle the affordability of health care, and whether the issue will be enough to translate into turnout and votes, remains an open question.

Health Care Has Been Among the Top Electoral Issues, Especially Following Periods of National Debate

National exit polls from elections over the past several decades show that voters ranked health care among their top concerns, but “the economy” was the number one issue in most elections. While exit polls usually ask voters to choose between health care and the economy as separate issues, KFF polling has long shown that health care costs are a key economic concern for the public. Analysis of exit poll data also show that health care has been more top-of-mind for voters immediately following periods of national debate on health care reform, such as in elections held during President Clinton’s presidency (1992-1998) and later during President Obama’s presidency (2008-2016) and the passage of the Affordable Care Act (ACA) in 2010. In these instances, health care costs were key health care issues, with political debate centering around affordability. But in the past three decades of exit polls, health care itself has only been ranked the number one issue by voters once, during the 2018 midterms after Republican attempts to repeal and replace the ACA failed dramatically in the Senate. Since 2020, health care has remained among the top issues, with the focus in some elections on specific health care issues such as COVID-19 or abortion access.

Figure 1

Democratic Voters Are More Likely to Say Health Care Is Important to Their Vote

Notably, Democratic voters have typically been more likely than Republican voters to cite health care issues as important in pre-election KFF Health Tracking Polls. For example, in 2018, when health care was the number one issue for all voters, about one third (34%) of Democratic voters said it was important for 2018 candidates to talk about health care, compared to one in five (20%) Republicans who said the same. In more recent elections when health care issues focused on specific topics like abortion rights and COVID-19, between a quarter and half of Democratic voters picked these issues, versus about one in ten, or fewer, Republican voters.

Democrats Have Historically Had Advantage on Health Care, Republicans on the Economy

While “the economy” tends to almost always have the top billing in election poll issue rankings, KFF polls have consistently found that the cost of health care is an important part of people’s economic concerns. Indeed, recent KFF polls have found that health care costs are a top economic worry, with many adults saying they have difficultly affording these costs, they are burdened by health care debt, or that they delay or skip care due to high costs. Given that health care costs sit at the intersection of both health care and the economy, who do voters say they trust on this issue?

When it comes to presidential elections, KFF Health Tracking Polls and other polls have found that voters often say the Democratic candidate is better suited to handle health care, while the Republican candidate is better suited to handle the economy. In the 2012 and 2016 elections, President Obama and Secretary Clinton had more than 10-percentage point leads over Governor Romney and President Trump respectively in the share of voters who said they trusted each on health care. When it comes to the economy, President Obama had a 7-percentage point advantage over Governor Romney in 2012, but in subsequent elections, President Trump has had an advantage over each of his Democratic opponents. These leads were narrow over Secretary Clinton in 2016 and President Biden in 2020, but widened to a 15-percentage point lead over Vice President Harris in 2024.¹

Figure 3

In an era of hyper-partisan politics, KFF Health Tracking Polls conducted in the lead up to elections find that most voters tend to trust their own party to handle the direction of key issues. But among voters overall and among independent voters, the Democratic party has typically had an advantage over the Republican party when it comes to health care costs. For example, in surveys conducted in election years from 2012 to 2023, the Democrats had an advantage of thirteen percentage-points or less over Republicans on lowering health care costs. But in 2023, about six in ten voters said they trust the Democrats on the affordability of health care, compared to about four in ten who said they trust the Republicans.

Figure 4

Implications for the 2026 Midterm Elections

While there are many months before the midterm elections and events such as the war in Iran may shift electoral concerns, recent KFF pre-election polls show the public remains concerned about the number one issue of the 2024 election: the economy. But recent polls also suggest that the role of health care costs among voters’ economic concerns appears to be on the rise compared to previous election cycles. In 2024 polling from AP Votecast, when voters were specifically asked about which household costs they were “very concerned” about, the cost of food and groceries took the top spot across partisans (67% of total voters), and health care costs (54% of total voters) ranked second for Democratic and independent voters.

In more recent KFF polling from January 2026, health care costs are now voters’ top economic concern (31% of total voters say they are “very worried”). This is the case across partisanship, with substantial shares of Democrats (33%), independents (36%) and Republicans (25%) saying they are “very worried” about being able to afford health care for themselves and their families. 

In January of this year, about one in four voters also said they feel their health care costs are increasing faster than other household expenses, such as food and utilities, and looking ahead, a majority (58%) said they expect health care costs for them and their families to become less affordable next year. In addition, in March, a majority (59% of the public; 57% of voters) say they are worried about affording prescription drugs for themselves and their families, the largest share since KFF first polled on this question in 2018.

The rising concern about health care costs has occurred at a time when health insurance premiums and cost-sharing for employer-sponsored insurance are on the rise, with the average annual premium for family health coverage rising 6% to nearly $27,000 in 2025. At the same time, the policy debate and government shutdown over the ACA enhanced tax credits have put a spotlight on increasing health care costs for ACA marketplace enrollees.

Amid this environment, there are signs that Democrats may now be viewed as more trustworthy than they were in 2024, when President Trump (the Republican candidate) won more votes than Vice President Harris (the Democratic candidate) among voters who said they were “very concerned” about health care costs (54% vs. 44%). Now, KFF polling from March 2026 finds Democrats have an advantage over Republicans for who voters trust to address the cost of health care (40% vs. 28%) and the cost of prescription drugs (38% vs. 28%), with about one in four voters saying they trust “neither party” on these issues.

Democrats maintain an advantage on health care and prescription drug costs among independent voters as well. But notably, the share saying they trust “neither party” rises to about four in ten among independent voters, larger than the shares who say they trust either the Democrats or the Republicans. The sizeable shares of independent voters, as well as voters overall, who say they trust neither party suggests that both parties may still be able to make inroads with voters on the issue of health care affordability before the midterm elections. But it also illustrates that there might be a lack of enthusiasm for candidates on this issue and may suggest that some voters may choose to stay home if they don’t feel either party can address this core issue.

While voter trust and the perceived importance of health care costs matter for the midterm election, a key factor is how strongly the issue motivates voters to turn out. The 2026 campaigns are just beginning, but health care costs seem to be motivating voters across party lines. As of January 2026,  about two-thirds of Democratic voters and just less than half of independent voters said health care costs will have a “major impact” on both their decision to vote and which party’s candidate they will support. On the other hand, about one in four Republican voters also said health care costs will have a “major impact” on their voting choices, and an additional third said it will have a “minor impact,” suggesting the issue is motivating Republicans as well.

1. In 2012, question wording was, “Which presidential candidate, Barack Obama or Mitt Romney, do you trust to do a better job… lowering health costs for people like you?” and “…dealing with the economy and jobs?”
    
   In 2016, question wording was, “Thinking about the candidates for president in 2016, regardless of political party or who you intend to vote for, which candidate do you trust to do a better job dealing with access and affordability of health care, Donald Trump or Hillary Clinton?” and “Regardless of which presidential candidate you support, please tell me if you think Hillary Clinton or Donald Trump would better handle each of the following issues…The Economy.”
    
   In 2020, question wording was, “Thinking about the candidates for president in 2020, regardless of political party or who you intend to vote for, which candidate do you trust to do a better job… dealing with health care, Donald Trump or Joe Biden?” and “…the economy.”
    
   In 2024, question wording was, “Regardless of who you intend to vote for in the upcoming elections, which presidential candidate do you trust to do a better job dealing with each of the following?” “The economy and inflation” and “Health care costs, including prescription drug costs.” ↩︎