NIH-Supported Research Examines HIV Prevention Tools For Women In Africa

NIH: Most women use vaginal ring for HIV prevention in open-label study
“In an open-label study of women in southern and eastern Africa, a vaginal ring that is inserted once a month and slowly releases an antiviral drug was estimated to reduce the risk of HIV by 39%, according to statistical modeling. In addition, the study found that participants appeared to use the ring more in the open-label study than in a previous clinical trial. These and other results of the HIV Open Label Extension (HOPE) study were presented [Tuesday] at the 10th IAS Conference on HIV Science (IAS 2019) in Mexico City…” (7/23).

NIH: PrEP use high but wanes after three months among young African women
“In a study of open-label Truvada as daily pre-exposure prophylaxis (PrEP) to prevent HIV among 427 young African women and adolescent girls, 95% initiated the HIV prevention strategy, and most used PrEP for the first three months. However, PrEP use fell among participants in this critical population during a year of follow-up clinic visits, although HIV incidence at 12 months was low. The preliminary results suggest that tailored, evidence-based adherence support strategies may be needed to durably engage young African women in consistent PrEP use…” (7/23).