In a post in the ONE blog, Rajat Goyal, India country director at the International AIDS Vaccine Initiative, reflects on progress in the global AIDS response, which he attributes largely to the development of and improved access to antiretroviral medicines, and he examines the need for a vaccine in order to bring an end to the epidemic. “More than 6,000 people worldwide are newly infected with HIV every day, and the pandemic is still spreading faster than the drugs to treat and prevent it: more people are newly infected each year than gain access to treatment,” he notes, adding, “In this context, it is clear that to ‘end AIDS’ we must not only provide more of what works, but also develop a vaccine” (12/3).