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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • Assessing PEPFAR’s Impact: Analysis of Mortality in PEPFAR Countries

    Issue Brief

    As the PEPFAR program approaches its two-decade mark, this new analysis finds the program was associated with large declines in mortality in PEPFAR recipient countries since its creation in 2003, suggesting that future investments will continue to yield significant health impacts.

  • Tracking Global COVID-19 Vaccine Equity: An Update

    Issue Brief

    This updated analysis looks at global COVID-19 vaccination efforts by income-level and region to assess the equity gap in both vaccination coverage and rates of administration. Overall, we find that low-income countries and countries in Africa are lagging behind, and based on current rates, are unlikely to meet global vaccination targets.

  • Tracking U.S. COVID-19 Vaccine Donations

    Issue Brief

    This analysis assesses U.S. COVID-19 vaccine dose donations in order to gauge progress towards meeting stated global vaccination goals.

  • The Public’s Awareness Of and Concerns About Coronavirus

    Issue Brief

    The February 2020 KFF Health Tracking Poll examines the public's awareness of and concerns about the Coronavirus, following its spread across China and around the globe. The public is concerned about the potential economic and health impacts of the virus on the U.S. and on them and their families. A majority of the public and majorities across partisans say the U.S. is currently doing enough to prevent the spread of the virus.

  • White House Releases FY21 Budget Request

    Fact Sheet

    The White House released its FY 2021 budget request to Congress on February 10, 2020, which includes significant cuts to global health programs compared to the FY 2020 enacted levels. In addition, in some cases, these cuts are steeper than those proposed by the Administration in last year’s request.

  • Testimony: The U.S. Government Role in Women’s Global Health and Key Challenges

    Issue Brief

    Jennifer Kates, Senior Vice President and Director of KFF’s Global Health & HIV Policy program, testified before the U.S. House of Representatives’ Committee on Foreign Affairs as part of a hearing on Unique Challenges Women Face in Global Health. Her testimony describes the role of the U.S. government in women’s global health and highlights challenges and opportunities to strengthen these efforts.

  • Analysis: Global Health Funding in the FY15 Omnibus Appropriations Act 

    News Release

    The FY15 Omnibus Appropriations Act contains $5.4 billion in emergency funding to address the Ebola crisis – a significant increase in total U.S. support for global health. Aside from the additional funding for Ebola, global health funding remained essentially flat at $9.2 billion, according to a new Kaiser Family Foundation funding analysis.