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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • NGO Engagement in U.S. Global Health Efforts: U.S.-Based NGOs Receiving USG Support Through USAID

    Report

    This report provides an analysis of U.S.-based non-governmental organizations (NGOs) that received global health funding from the U.S. government (USG) during FY 2013. It specifically focuses on funding provided to NGOs by the U.S. Agency for International Development (USAID), the largest implementer of global health activities among USG agencies and departments.

  • What Could U.S. Budget Cuts Mean for Global Health?

    Issue Brief

    President Trump’s fiscal year 2018 budget request would cut global health programs by approximately $2.5 billion. This analysis models the potential impact of the Administration’s proposed budget, as well as two budget scenarios with more modest decreases.

  • Breaking Down the U.S. Global Health Budget by Program Area

    Fact Sheet

    The U.S. government is the largest donor to global health in the world. This fact sheet breaks down the U.S. global health budget by program area: HIV/PEPFAR; tuberculosis; malaria/the President's Malaria Initiative; the Global Fund to Fight AIDS, Tuberculosis, and Malaria; maternal & child health; nutrition; family planning & reproductive health; global health security; and neglected tropical diseases.

  • Blended Finance for Global Health: Summary of a Policy Roundtable

    Issue Brief

    Blended finance is the subject of increasing attention and growing excitement in global health. Our new brief provides background on this development funding approach, and presents key takeaways from a policy roundtable discussion we held earlier this year.

  • New Online Resource Tracks Legislation Affecting Global Health 

    News Release

    A new KFF online resource tracks more than 30 bills introduced in the current Congress that would affect global health policy. The U.S. Global Health Legislation Tracker covers current legislation on an array of topics, from implementing a strategy to help end preventable maternal and child deaths to creating an action plan on climate change.

  • The Current Ebola Outbreak and the U.S. Role: An Explainer

    Issue Brief

    An outbreak of Ebola is currently ongoing in the Democratic Republic of Congo (DRC), now the second largest Ebola epidemic ever recorded. This Issue Brief gives an overview of the current situation, explains the U.S. role in responding to the outbreak, and answers key questions about the broader global response.