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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • U.S. Global Health Budget Tracker

    Feature

    This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

  • The Dangers of Vaccine Disillusionment

    Perspective

    In this Foreign Affairs article, Josh Michaud and Jen Kates lay out the challenges in vaccinating people in low-income countries around the world and review early plans to ensure safe and effective vaccines are made available and delivered to people across the globe.

  • The Role of NGOs in the U.S. Global Health Response

    Issue Brief

    This data note helps shed light on the role of non-governmental organizations (NGOs) in the U.S. global health response. Using updated data and building on earlier Kaiser Family Foundation reports, it paints a fuller picture of the role of these key implementers of U.S. global health programs and discusses key policy questions going forward.

  • Global COVID-19 Vaccine Equity: U.S. Policy Options and Actions to Date

    Issue Brief

    This brief examines U.S. policy options for helping expand global access to COVID-19 vaccines, focusing on four main areas: in-kind donations of vaccine doses, additional funding for global access mechanisms like COVAX, helping expand global vaccine manufacturing, and relaxing or waiving intellectual property protections on vaccine technologies. We summarize what the administration has done to date in these areas and policy issues related to each.

  • Putting U.S. Global COVID-19 Vaccine Donations in Context

    Policy Watch

    While some have praised the most recent U.S. donation announcement as an important development, others have said the U.S. could do much more, pointing to the large supply of doses the U.S. is building up and the slowing demand for vaccinations in the country.  In this policy watch, we sought to put the U.S. pledge of 80 million doses in further context.

  • White House Releases Full FY 2022 Budget Request

    Fact Sheet

    President Biden released his full FY 2022 budget request to Congress on May 28, 2021 (an initial, topline discretionary FY 2022 budget proposal was released on April 9, 2021). The request includes an increase of almost $1 billion for global health programs, most of which (84%) is for global health security.