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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • New Online Resource Tracks Donor Funding for Coronavirus Response

    News Release

    While donors have begun providing support to China and other low- and middle-income countries, there is currently no other centralized repository for this information. This tracker provides an accounting of publicly available information on donor funding to date.

  • How Many Adults Are at Risk of Serious Illness If Infected with Coronavirus? Updated Data

    Issue Brief

    About four in ten adults (37.6%) ages 18 and older in the U.S. (92.6 million people) have a higher risk of developing serious illness if they become infected with the novel coronavirus, due to their older age (65 and older) or health condition. The share who have a higher risk varies across the country. An estimated 5.1 million of these adults are uninsured.

  • What Do We Know About Children and Coronavirus Transmission?

    Issue Brief

    As schools prepare for Fall, this brief examines what's known about children and COVID-19, including the risk the virus poses to children and the risk of children becoming infected and transmitting to others, and the experiences of other countries that reopened classrooms.

  • Foreign Policy and Global Health Experts on the USG’s Role in Global Health

    Issue Brief

    While global health has enjoyed significant bipartisan support among US policymakers over the past 15 years, the potential for changes in the political landscape in 2016 makes this an opportune time to assess the USG’s position relative to global health needs and funding. With this in mind, the Kaiser Family Foundation’s Global Health Policy Program asked Hart Research Associates and Public Opinion Strategies to solicit the views of specialists in foreign policy and global health.

  • Zika Virus: The Challenge for Women

    Perspective

    In the latest post in the Policy Insights series, Jen Kates, Josh Michaud, and Allison Valentine examine how rapid emergence of Zika virus in the Americas, and its association with a severe birth defect, impact women as some health officials are calling for women to avoid pregnancy even though they have limited reproductive health access in some of the affected countries. They also examine the role of the U.S. government in addressing Zika and its impact on women in Latin America and the Caribbean.

  • The COVAX Humanitarian Buffer for COVID-19 Vaccines: Review and Assessment of Policy Implications

    Issue Brief

    In this Issue Brief we review and assess the COVAX Humanitarian Buffer mechanism, which is part of the effort to share Covid vaccines globally. The Buffer is intended to direct vaccines to vulnerable people like refugees and others facing humanitarian emergencies during the pandemic, and was supported by the US and many other donors and organizations. However, it faced many challenges such as liability and indemnification issues for using newly developed vaccines, restricted access to vaccines and funding, and difficult and complex application, review, and implementation processes. We discuss these challenges and also consider implications of the Buffer experience for future pandemic preparedness and response efforts.

  • PEPFAR May Improve Key Economic and Educational Outcomes, Not Just Health Outcomes

    News Release

    A new KFF analysis finds that the President’s Emergency Plan for AIDS Relief (PEPFAR), the U.S. global HIV/AIDS response and the largest commitment by any nation to address a single disease in history, is associated with improvements in key economic and educational outcomes in countries that received PEPFAR support.

  • PEPFAR Reauthorization on the Horizon

    Perspective

    In this Think Global opinion piece, Jennifer Kates and Kellie Moss discuss what could happen if the United States’ signature initiative on global health is not reauthorized.