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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • The XIII International AIDS Conference

    Other Post

    , July 9-14, 2000 In Durban, South Africa, more than 10,000 delegates gathered to discuss critical HIV/AIDS issues such as progress in medical research, access to treatment and care, HIV prevention, and governmental and private sector support for the fight against AIDS.

  • Poll: Ebola Was a Bigger Story Than the Midterms

    News Release

    In his latest column for The Wall Street Journal’s Think Tank, Drew Altman discusses what the public was more concerned about in November, Ebola or the results of the midterm elections. All previous columns by Drew Altman are available online.

  • Global Financing for Malaria: Trends & Future Status

    Report

    This report finds that funding for global malaria control and elimination activities has risen from US$871 million in 2005 to US$2.6 billion in 2013. However, total funding is significantly below US$5.1 billion, the goal set by the Global Malaria Action Plan, which is a framework endorsed by world leaders in 2008 to reach global malaria reduction targets.
    Additionally, support for malaria research and development (R&D) activities in 2013 was estimated to be US$549 million, below the estimated annual need of US$750-900 million and the lowest level of funding since 2007, the first year of available data.

  • Global Health Interventions: A Review of the Evidence

    Interactive

    Global Health Interventions: A Review of Evidence (GHIR) provides policy-relevant and accessible information on the efficacy (the "what works") of key global health interventions, including the strength of the evidence.

  • Chartpack: Trends in U.S.-Funding for HIV/AIDS

    Report

    This chartpack, "Trends in U.S. Government Funding for HIV/AIDS," provides an analysis of U.S. federal funding for HIV/AIDS since fiscal year (FY) 1981. It presents data and trends in the major categories of funding -- care, cash and housing assistance, research, prevention, and global/international -- over time.