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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • An Update on PEPFAR Reauthorization

    Policy Watch

    This Policy Watch provides an update on the status of PEPFAR reauthorization, which expired on March 25, 2025, allowing certain provisions to lapse.

  • KFF Coronavirus Poll: March 2020

    Feature

    Fielded from March 11-15, this KFF Coronavirus poll provides a snapshot of the public’s experience, knowledge and views about the coronavirus, also known as COVID-19, during the rapidly unfolding crisis. A majority of Americans say they are taking precautions to protect themselves by the novel coronavirus pandemic but the public worries about the health and economic consequences as the situation evolves in the coming months.

  • The Public’s Awareness Of and Concerns About Coronavirus

    Issue Brief

    The February 2020 KFF Health Tracking Poll examines the public's awareness of and concerns about the Coronavirus, following its spread across China and around the globe. The public is concerned about the potential economic and health impacts of the virus on the U.S. and on them and their families. A majority of the public and majorities across partisans say the U.S. is currently doing enough to prevent the spread of the virus.

  • Tracking Global COVID-19 Vaccine Equity

    Issue Brief

    This analysis looks at global COVID-19 vaccination efforts by income-level and region to assess the equity gap in both vaccination coverage and rates of administration. Overall, we find that low-income countries and countries are lagging behind, and based on current rates, are unlikely to meet global vaccination targets.

  • Funding for Key HIV Commodities in PEPFAR Countries

    Issue Brief

    In many low- and middle-income countries, PEPFAR and the Global Fund are significant funders of commodities to diagnose, treat, and prevent HIV, along with country governments. But, information on their relative contributions, which is important for assessing the HIV response, is not readily available. We analyzed data from PEPFAR documents on funding for key HIV commodities in 34 PEPFAR countries to better understand the funding landscape.