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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • Global Children’s Health and Mortality Tutorial

    Interactive

    This tutorial was produced for kaiserEDU.org, a Kaiser Family Foundation website that ceased production in September 2013. The kaiserEDU.org tutorials are no longer being updated but have been made available on kff.org due to demand by professors who are using the tutorials in class assignments. You may search for other tutorials to view on kff.org.

  • A Global Perspective on Women’s Health Tutorial

    Interactive

    This tutorial was produced for kaiserEDU.org, a Kaiser Family Foundation website that ceased production in September 2013. The kaiserEDU.org tutorials are no longer being updated but have been made available on kff.org due to demand by professors who are using the tutorials in class assignments. You may search for other tutorials to view on kff.org.

  • The Current State of the Global HIV/AIDS Epidemic Tutorial

    Interactive

    This tutorial was produced for kaiserEDU.org, a Kaiser Family Foundation website that ceased production in September 2013. The kaiserEDU.org tutorials are no longer being updated but have been made available on kff.org due to demand by professors who are using the tutorials in class assignments. You may search for other tutorials to view on kff.org.

  • Global COVID-19 Vaccine Access: A Snapshot of Inequality

    Policy Watch

    This policy watch examines global access to COVID-19 vaccines by country income level, assessing country income levels' shares of purchased doses and potential vaccination coverage, while also looking closely at the potential impact of COVAX in addressing vaccine access disparity between high-income and low- and middle-income countries.

  • Key Issues and Questions for PEPFAR’s Future

    Issue Brief

    This brief explores key issues and poses questions regarding PEPFAR’s future, providing a roadmap for the major decisions ahead for the program. It identifies eight key, interrelated issues facing the administration, Congress, and other PEPFAR stakeholders.

  • A Year of Vaccine Inequity

    Feature

    Just 7% of low-income countries' populations have received at least one dose of a COVID-19 vaccine as of December 20, well behind the 40% target for 2021.

  • The U.S. Government and Gavi, the Vaccine Alliance

    Fact Sheet

    This fact sheet examines Gavi, the Vaccine Alliance (also known as Gavi), an independent, public-private partnership and multilateral funding mechanism that aims to increase access to immunization in lower income countries, and explores the role the U.S. government plays in supporting the partnership.

  • HIV Policy Alignment with International Standards in PEPFAR Countries

    Issue Brief

    This issue brief assesses how the HIV policy landscapes in PEPFAR countries compare to international standards and recommendations. Additionally, we look at the HIV policy landscapes in PEPFAR countries as compared to peer countries. These comparisons are done at the overall, category, and policy indicator level.