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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • Visualizing Health Policy Infographic: A Snapshot of US Global Health Funding  

    News Release

    This month's Visualizing Health Policy infographic shows global health funding's share of the US federal budget, the flattening of US funds for global health during the 21st century, where US dollars for global health are spent, the major areas receiving US global health funding, and how the US public overestimates the percentage of the federal…

  • Global Health Funding in the FY 2024 Final Appropriations Bill

    Fact Sheet

    Updated: March 25, 2024 On March 23, 2024, the President signed the second package of final FY 2024 appropriations bills, otherwise known as the “Further Consolidated Appropriations Act, 2024,” which was released by the House and Senate Appropriations Committees on March 20, 2024, passed by the House on March 22, 2024 and passed by the…

  • International Comparison of Health Systems

    Feature

    This Health Policy 101 chapter explores the performance of the U.S. health system on a number of cost, outcomes, and quality measures by comparing it with those in similarly large and wealthy OECD nations. It highlights that despite significant spending, Americans have shorter life expectancies and encounter more barriers to health care, influenced by both the health system's structure and broader socioeconomic factors.

  • What the Election Could Mean for the Mexico City Policy and U.S. Foreign Aid

    Issue Brief

    This analysis outlines the potential reach of a prominent conservative proposal — widely seen as a blueprint for another Trump administration — that recommends expanding the Mexico City Policy to include virtually all U.S. foreign assistance. It looks at the amount of funding, the number of organizations, the range of foreign assistance sectors, and other variables that could be affected should the proposal be implemented.

  • A Little-Noticed Win in Global HIV Treatment

    News Release

    In his latest column for The Wall Street Journal's Think Tank, Drew Altman discusses a recent success in global HIV treatment and how successes may get less attention than they deserve because of prevailing attitudes about the corruption in foreign aid. All previous columns by Drew Altman are available.

  • Reading the Tea Leaves on U.S. Global Health Policy

    Perspective

    In this Policy Insight, Jen Kates and Josh Michaud look at the prospects for the future of U.S. global health policy, examining whether long-term bipartisan support may be tested during a time of political transition, and identifying key areas of consensus among policymakers and the public.

  • Zika Virus: The Challenge for Women

    Perspective

    In the latest post in the Policy Insights series, Jen Kates, Josh Michaud, and Allison Valentine examine how rapid emergence of Zika virus in the Americas, and its association with a severe birth defect, impact women as some health officials are calling for women to avoid pregnancy even though they have limited reproductive health access in some of the affected countries. They also examine the role of the U.S. government in addressing Zika and its impact on women in Latin America and the Caribbean.