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America First MOU Bilateral Global Health Agreements

On September 18, 2025, the U.S. government released its new America First Global Health Strategy, which details how the U.S. will engage in global health efforts moving forward. As part of this new strategy, the United States announced that it will be establishing bilateral health cooperation agreements with countries that receive U.S. global health assistance via Memorandums of Understanding (MOUs)

This tracker provides an overview of the MOUs signed to date. Data are based on press releases issued by the State Department, as specific details provided in the MOUs (i.e. program areas, financial breakdowns, data or specimen sharing agreements, etc.) are not yet publicly available. The tracker will be updated as agreements are signed and more data become available.

Questions for the America First Global Health Strategy

Global Health Budget Summaries

Overview of President Trump’s Executive Actions on Global Health

The Pause of Foreign Aid and Implications for PEPFAR and Other Global Health Programs

selected resources

Global Health Aid Cuts

This collection of resources chronicles what recent Trump administration global health aid cuts mean for the future of global health programs and the people who rely on them.

A promotional image for the the KFF Health Policy 101 U.S. Government and Global Health

The U.S. Government and Global Health

In this Health Policy 101 chapter, investigate the U.S. role in global health, including the major initiatives the United States supports, funding levels, and agencies involved in implementing program area efforts.

the essentials

Global Health Trackers

U.S. Global Health Budget Tracker

This tracker provides regularly updated information on U.S. government funding for global health. It includes historical trends and tracks funding levels for U.S. global health efforts through bilateral and multilateral contributions and by program area and agency.

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  • Mapping the Donor Landscape in Global Health: HIV/AIDS

    Report

    This report maps the complex network of international assistance aimed at addressing the global impact of HIV/AIDS, looking both at donor governments and multilateral organizations. It seeks to provide perspective on the geographic presence of global health donors and to enable more effective coordination and delivery of services globally and within individual recipient nations. This report is the first in a series that will examine donor presence and magnitude of assistance by issue area, region and country.

  • CSIS Task Force on HIV/AIDS

    Report

    The Center for Strategic and International Studies (CSIS) Task Force on HIV/AIDS, co-chaired by Senators Bill Frist (R-TN) and Russell Feingold (D-WI), outlines strategic choices that the United States faces in fighting the global HIV/AIDS pandemic.

  • Donor Funding for Health in Low – and Middle – Income Countries, 2001-2007

    Report

    Donor governments, including the United States and European nations, provide the bulk of international funding for health in low- and middle- income countries each year. Despite significant increases in such funding, however, it still falls short of need as estimated by the World Health Organization’s Commission on Macroeconomics and Health.

  • The U.S. Government’s Global Health Policy Architecture: Structure, Programs and Funding

    Report

    This report provides the first comprehensive look at the U.S. government agencies and programs involved in the nation’s global health response, including their funding and their approaches. The report also provides overviews of the large-scale global health initiatives of the U.S. government, information on which countries receive support from the U.S., and a review of the key laws governing U.S. global health policy and relevant Congressional committees.

  • U.S. Global Health Policy: In Focus “IOM Final Report on the U.S. Commitment to Global Health”

    Event Date:
    Event

    During this webcast, members of the Institute of Medicine's committee on the U.S. Commitment to Global Health discussed the committee's final report that concluded that the U.S. government and U.S.-based foundations, universities, nongovernmental organizations, and commercial entities have an opportunity to improve global health and provided specific recommendations for how these groups should proceed.

  • 2012 Survey of Americans on the U.S. Role in Global Health

    Report

    The 2012 Survey of Americans on the U.S. Role in Global Health is the fourth in a series that aims to examine the American public’s views, knowledge and opinions of U.S. efforts to improve health for people in developing countries.