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  • The Global HIV/AIDS Epidemic

    Fact Sheet

    This updated fact sheet provides the latest data on the global HIV/AIDS epidemic, including impact on affected and vulnerable populations, treatment and prevention efforts, and an overview of the U.S. and global responses to the epidemic.

  • The U.S. Government and Gavi, the Vaccine Alliance

    Fact Sheet

    This fact sheet examines Gavi, the Vaccine Alliance (also known as Gavi), an independent, public-private partnership and multilateral funding mechanism that aims to increase access to immunization in lower income countries, and explores the role the U.S. government plays in supporting the partnership.

  • The International Health Regulations and the U.S.: Implications of an Amended Agreement

    Issue Brief

    This brief reviews the proposed revisions to the World Health Organization-based agreement known as the International Health Regulations (IHR), and the implications for the U.S. WHO member states are expected to adopt the revised IHR at the World Health Assembly meeting this year. The U.S. government has been a leading proponent of many of the expected revisions to the IHR. In this analysis we also evaluate some of the criticisms of the revisions to the IHR.

  • The U.S. Government and Global Health

    Feature

    This Health Policy 101 chapter outlines the U.S. government's efforts in global health, which aim to improve health in low- and middle-income countries while supporting U.S. global development, national security, and foreign policy goals. As the largest funder of global health programs worldwide, the U.S. provides bilateral and multilateral support to address major global health areas such as HIV and maternal and child health. Key issues addressed include U.S. global health leadership in a challenging U.S. political and budget environment, helping countries prepare for unexpected health challenges, and sustainability in the context of weak health systems and equity challenges.

  • The ‘Pandemic Agreement’: What it is, What it isn’t, and What it Could Mean for the U.S.

    Issue Brief

    Countries are seeking to create a new 'pandemic agreement' at WHO to strengthen pandemic prevention, preparedness, and response. This brief explains what the pandemic agreement is, where the U.S. stands on issues included in the agreement, and potential outcomes of the ongoing negotiations. It also evaluates several criticisms of the agreement and the evidence for each.

  • The U.S. Government and Global Health Security

    Issue Brief

    This brief examines the U.S. government's efforts in global health security—that is, activities to help countries prepare for and develop capacities to address epidemic and pandemic diseases. It provides history and background, outlines the U.S. agencies carrying out these efforts, describes funding, and highlights key policy issues going forward.

  • The New Pandemic Fund: Overview and Key Issues for the U.S.

    Issue Brief

    This brief offers an overview of the new multilateral global health financing mechanism known as the Pandemic Fund, which is housed at the World Bank. The brief reviews the evolution of the Fund, its current financial status and donors, U.S. engagement, and policy issues going forward.

  • Africa CDC: Its Evolution and Key Issues for its Future

    Issue Brief

    This Issue Brief reviews the history of Africa CDC, describing its structure, funding and operations to date, including U.S. government engagement, as well as challenges and opportunities for the institution moving forward.

  • Assessing the Role of Treaties, Conventions, Institutions, and Other International Agreements in the Global COVID-19 Response: Implications for the Future

    Issue Brief

    This issue brief examines existing treaties and other global health agreements to assess whether they have been utilized for the COVID-19 pandemic response and whether they contain pandemic preparedness and response components in their mandates. The COVID-19 pandemic challenged and revealed gaps in global health governance systems, prompting stakeholders to reevaluate existing frameworks and discuss new agreements aimed at addressing future pandemics. To help inform these discussions, we evaluate existing global health agreements to assess their role in pandemic preparedness and response efforts, including the COVID-19 pandemic.

  • The COVAX Humanitarian Buffer for COVID-19 Vaccines: Review and Assessment of Policy Implications

    Issue Brief

    In this Issue Brief we review and assess the COVAX Humanitarian Buffer mechanism, which is part of the effort to share Covid vaccines globally. The Buffer is intended to direct vaccines to vulnerable people like refugees and others facing humanitarian emergencies during the pandemic, and was supported by the US and many other donors and organizations. However, it faced many challenges such as liability and indemnification issues for using newly developed vaccines, restricted access to vaccines and funding, and difficult and complex application, review, and implementation processes. We discuss these challenges and also consider implications of the Buffer experience for future pandemic preparedness and response efforts.