In this PLoS Medicine research article, Reed Beall and Randall Kuhn of the Josef Korbel School of International Studies at the University of Denver provide an analysis of trends in compulsory licensing (CL) of pharmaceuticals since the Doha Declaration. “Almost 10 years after the Doha Declaration, we examined the subsequent occurrence of CL episodes, an important direct indicator of treaty impact,” they write. Given that “compulsory licensing activity has diminished greatly since 2006, … the researchers conclude, health advocates who pushed for the Doha Declaration reforms have had little success in engaging trade as a positive, proactive force for addressing health gaps,” according to the article’s Editors’ Summary (1/10).