Gene Mutations Conferring HIV Protection Might Shorten Lifespan, Study Shows; Scientists Warn Against Gene Edits Using CRISPR
Nature: Gene edits to ‘CRISPR babies’ might have shortened their life expectancy
“The scientist who edited the genomes of twin girls in an attempt to make them resistant to HIV might have inadvertently shortened their life expectancy. People with two disabled copies of the CCR5 gene — the version that protects against HIV infection — are 21% more likely to die before the age of 76 than are people with at least one working copy of the gene, according to a study published on 3 June in Nature Medicine. The reason for the discrepancy is unknown…” (Reardon, 6/3).