New England Journal of Medicine: PEPFAR — 15 Years and Counting the Lives Saved
Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID) at NIH, and Robert W. Eisinger, special assistant for scientific projects at NIAID

“…[PEPFAR] has had an unprecedented impact on the pandemic of HIV and AIDS. … PEPFAR has received continuous bipartisan support from Congress since 2003 and is the largest global health initiative for a single infectious disease that has ever been implemented. … PEPFAR has … provided some of the critical workforce, organizational, and physical infrastructure to address other concerns — such as malaria, tuberculosis, maternal and child health, immunizations, and unanticipated infectious disease outbreaks — that affect the geographic areas where patients with HIV are treated. … With regard to international public relations, PEPFAR has done as much as or more than any other program in enhancing the humanitarian image of the United States and has firmly established it as a key player in the response to a historic global public health crisis. … Over the past 15 years, PEPFAR has demonstrated the transforming results that can be realized by strong government leadership in the global health arena. It is entirely possible to bring the HIV/AIDS pandemic to an end, and PEPFAR will undoubtedly play an essential role in this endeavor. However, it is vital that support for this transformative program continue both to meet the immediate challenge of HIV/AIDS and to serve as the model for the control and elimination of other globally devastating infectious diseases” (1/25).