Tuberculosis

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MSF Publishes List Of Top 10 Stories Of 2011 About Access To Medicine

This Medecins Sans Frontieres (MSF) special report highlights the top 10 stories of 2011 regarding access to essential medicines, according to MSF. The list includes the findings of the HPTN 052 clinical trial, which “show that providing people with HIV treatment early not only saves their lives but can reduce the risk…

More Work Ahead In TB Drug Development, Treatment Delivery

The U.S. Food and Drug Administration’s approval of the tuberculosis (TB) drug Sirturo, also known as bedaquiline, “appears to be just the first step in an exciting renaissance for TB drug development,” Mark Harrington, executive director of Treatment Action Group (TAG), writes in the Bill & Melinda Gates Foundation’s “Impatient Optimists” blog. “Another new drug, delamanid, is currently in late clinical trials and has been submitted to the European Medicines Agency for review as a treatment for [multidrug-resistant (MDR)] TB,” he notes. Harrington concludes, “It’s an exciting time for TB treatment, but much more needs to be done and more resources are needed. We need to focus not only on the discovery and development of new drugs, but also on ensuring that news drugs are delivered to those who need them and in combinations that can prevent the emergence of new types of drug resistance” (12/28).

Reflecting On FDA Approval Of New TB Drug

Noting “[t]he U.S. Food and Drug Administration (FDA) recently announced that it has approved a new treatment for multidrug-resistant [tuberculosis (TB)] that can be used as an alternative when other drugs fail,” Kim Lufkin, communications officer at the Global Health Technologies Coalition (GHTC), writes in the coalition’s “Breakthroughs” blog, “There is a pressing and urgent need for even more new TB drugs, which makes this new FDA approval so significant.” She continues, “It is also noteworthy that the FDA approved Sirturo under its accelerated approval program, in addition to granting the drug fast track, priority review, and orphan-product status,” adding, “It’s critical that the FDA continues to support its priority review, fast track, and similar programs, which can help speed access to safe and effective global health drugs” (1/3).

Integration Of TB/HIV Services Necessary To Beat ‘Twin Epidemics’

Swaziland “is struggling to overcome twin epidemics of HIV and tuberculosis (TB),” UNAIDS Executive Director Michel Sidibé writes in the Huffington Post “Healthy Living” blog. “Here in Swaziland, more than three-quarters of TB patients are also living with HIV, and TB is the leading cause of death among people with…

TB Survivor Calls On USAID To Expand Support For Global Health R&D

In a post in the Global Health Technologies Coalition’s “Breakthroughs” blog, part of a “new blog series to highlight the impact of USAID’s commitment to global health research and development (R&D),” Natalie Nelson, a tuberculosis (TB) survivor from Tennessee, in a Q&A calls for USAID to expand its support for…

Blog Reviews Recent IOM Report On Drug-Resistant TB

The Center for Global Health Policy’s “Science Speaks” blog reviews “the Institute of Medicine’s recent report on the global crisis of drug-resistant TB, itself a summary of a joint workshop hosted by the IOM and the Institute of Microbiology of the Chinese Academy of Sciences in Beijing earlier [in 2013].…

January 2014 Issue Of WHO Bulletin Available Online

The January issue of the WHO Bulletin features a news article on ending female genital mutilation, a research article on maternal health care in rural Zambia, and a policy and practice paper on designing drug regimens for drug-resistant TB, among other articles (January 2014).

Genetic Mutations Helping TB In Russia Spread More Efficiently

Nature: Russia’s drug-resistant TB spreading more easily “Bacterial ‘superbugs’ are getting ever more potent. Tuberculosis (TB) strains in Russia carry mutations that not only make them resistant to antibiotics but also help them to spread more effectively, according to an analysis of 1,000 genomes from different TB isolates — the…

Simultaneous Treatment For Patients With TB, AIDS Is More Effective, Study Says

New York Times: Treating Tuberculosis and AIDS Together Saves Lives “Patients who have multi-drug-resistant tuberculosis and AIDS are more likely to live if they get simultaneous treatment for both diseases rather than waiting weeks to start the AIDS treatment, a new study has found…” (McNeil, 2/17).

Nigeria Should Confront TB, With U.S. Assistance

Washington Post: Nigeria needs to confront another scourge: Tuberculosis David Bryden, TB advocacy officer for Results “…Nigeria’s frustratingly slow response to the Boko Haram abductions of more than 200 schoolgirls is mirrored by its apparent lack of attention to another crisis with deadly implications. Last year, a national survey showed…

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