In this post in The Hill’s “Congress Blog,” Kent Campbell, director of the Malaria Control Program at PATH, and Jonathon Simon, chair of the Department of International Health and director of the Center for Global Health and Development at the Boston University School of Public Health, write that “major progress has been made in the fight against malaria, thanks in large part to the efforts of the President’s Malaria Initiative (PMI),” and call the effort “a shining example of the profound impact the U.S. is making in global health.” They highlight a “recent external review of the first five years of its work,” which “shows substantial progress toward PMI’s goal of cutting malaria deaths by half in 15 African countries.”
Using a rodent model to examine the long-term effects of a potential malaria vaccine, a new study published in PLoS Biology by researchers at Penn State University shows that the vaccine could lead to the development of more virulent forms of malaria, the PLoS blog “Biologue” reports (Gross, 7/31). “Vicki Barclay, the study’s lead author, said it shows a need to track the long-term impact of any malaria vaccine, especially since any such vaccine is expected to be ‘leaky’ — meaning it won’t offer complete protection, and the disease will continue to spread, albeit at a slower rate,” CNN’s “The Chart” writes. “Researchers working with the leading candidate vaccine immediately questioned [the study], saying they’ve seen no sign of dangerous changes as a result of their work,” the blog continues (Hellerman, 8/1).
On the first stop of a 10-day tour of Africa, Secretary of State Hillary Clinton stopped at the Phillipe Maguilen Senghor Health Center in Dakar, Senegal, where Awa Marie Coll-Seck, the country’s minister of health, “explained to Secretary Clinton how these operational centers dramatically improve maternal and child health,” according to a post in USAID’s “IMPACTblog.” Coll-Seck “also noted that USAID-supported distribution of insecticide impregnated mosquito nets across the country had drastically reduced the incidence of malaria,” according to the blog, which adds that Clinton “was pleased to hear that the United States is playing a key role in helping meet one of its biggest challenges: decentralizing services so they are available at the village level throughout the country.” In an address several hours later, “Clinton invoked the Senghor center … saying she was highly impressed by the integrated nature of the facility” and that “[i]t was a successful model she hoped could be duplicated throughout Senegal and the entire West African region” (Taylor, 8/1).
With Africa’s “emerging position in the global order, … [a]stute African leaders are striving to ensure that this realignment delivers a new paradigm of partnership for sustainable health development — a partnership that is led by Africa, for Africans, through African-sourced solutions,” UNAIDS Executive Director Michel Sidibe writes in a Huffington Post “Impact Blog” opinion piece. The African Union is taking steps “to reduce the continent’s dependence on foreign solutions and foreign ‘aid’ while adopting and scaling up development solutions that have been proven to work in different African countries, and finding better and more sustainable approaches to financing them,” he states. “It makes a lot of sense to apply such an approach to addressing three killer diseases: AIDS, tuberculosis (TB) and malaria,” he continues, adding that “the overreliance of Africa’s AIDS response on foreign investments, foreign drugs and foreign solutions must be addressed.”
“African leaders have reaffirmed their commitment to efforts to eliminate malaria, after they were informed that unprecedented success in scaling up malaria control interventions resulted in one third reduction of malaria deaths in African in the last decade,” PANA/Afriquejet reports, adding “the leaders made the commitment at a high level meeting presided over by Liberian President Ellen Johnson Sirleaf, Chair of African Leaders Malaria Alliance (ALMA), in Addis Ababa, on the sidelines of the African Union (AU) summit which opened in the Ethiopian capital Sunday.”
“[A] surge in money for [insecticide-treated] nets and other interventions” to fight malaria over the past decade has reduced the malaria-related death rate by 26 percent since 2000, and a “new push” to fight the disease, which killed 655,000 people in 2010, would have beneficial results, according to a report set to be released by Ray Chambers, the U.N. special envoy for malaria, an Economist editorial notes. “But raising the cash will be tricky and getting the promised result harder still,” the editorial states. The African Leaders Malaria Alliance estimates that “[u]niversal deployment of good treatment, diagnostics and preventive measures, including bed nets, would — in theory — prevent 640 million malaria cases and three million deaths by 2015, the paper explains,” and notes “[t]his would cost at least $6.7 billion between 2012 and 2015,” the Economist writes.
“Many of Africa’s anti-malaria drugs are fake or of poor quality, weakening a crucial battle against the world’s deadliest disease, a new investigation has found,” GlobalPost reports, adding, “Many of the drugs — even those approved by the World Health Organization — are Chinese fakes or low-quality variants that failed quality tests, according to two new studies released today” (Conway-Smith, 7/10). “Two studies published in Research and Reports in Tropical Medicine suggested manufacturing problems, rather than counterfeiting, may be to blame for these substandard drugs in low- and middle-income countries around the world,” Agence France-Presse writes (7/10). Writing in a Business Day opinion piece published on Tuesday, “Roger Bate, lead author of the studies and a scholar at the conservative American Enterprise Institute, warned of ‘unthinkable’ public health consequences from drug resistance,” GlobalPost notes.
Health Ministers From Southeast Asia Asked To Support U.N. In Stemming Spread Of Drug-Resistant Malaria In Region
“Health ministers from the Association of Southeast Asian Nations (ASEAN) are being asked to support United Nations efforts to stem the spread of drug-resistant strains of malaria, especially along the borders of Cambodia and Burma,” VOA News reports. “Scientists fear resistant strains of malaria may spread beyond Southeast Asia, reaching continents such as Africa, a region with many victims of the mosquito-borne parasite,” according to the news service. “Thomas Teuscher, executive director of the United Nations-backed Roll Back Malaria Partnership (RBM), says more effort is needed to ensure that drug-resistant malaria at least remains localized in Southeast Asia,” VOA notes.
Cuban Company's Sales Of Larvicides To Fight Malaria-Carrying Mosquitoes In Africa Continue Despite U.N. Concern, Miami Herald Reports
The Cuban state-owned company Labiofam “is increasing sales of its mosquito larvicides to fight malaria in Africa, despite cautions by U.N. experts that such products have limited use and are not the most cost-effective method of attacking the disease,” the Miami Herald reports. The company’s website “says its larvicide Griselesf is used in anti-malaria programs in Ghana, Angola, Gambia, Tanzania, Nigeria, Burkina Faso, Equatorial Guinea, and Zambia,” according to the newspaper.
“[C]ooperation is essential to combat diseases that cross national borders,” Ramanan Laxminarayan, director of the Center for Disease Dynamics, Economics and Policy and a research scholar and lecturer at Princeton University, and Bryan Grenfell and Petra Klepac of Princeton University write in a SciDev.Net opinion piece. “This is not restricted to regional control — long-term, coordinated efforts that give neighboring countries an incentive to immunize or put in place other intervention measures can also lead to global elimination of a disease,” they write, discussing optimal vaccination strategies and disease control challenges.