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Sanofi Expects Dengue Vaccine Clinical Trial Results In September

Reuters: Sanofi faces make-or-break verdict on big dengue vaccine bet “Sanofi expects final clinical results for its vaccine against dengue by late September, the French drugmaker’s project leader has told Reuters, and has already gambled on starting production despite some disappointing early trials data. Sanofi has invested more than one…

Early Warning System Warns Of Dengue Risk In Brazil During World Cup

Reuters: Scientists warn of dengue fever risk during Brazil’s World Cup “The risk of an outbreak of dengue fever during the upcoming soccer World Cup in Brazil is serious enough to warrant a high alert in three of the 12 host cities, according to an early warning system for the…

Financial Times Features Special Report On NTDs

The Financial Times has published a special report (.pdf) on neglected tropical diseases (NTDs) featuring 10 articles examining issues including prevention, research, and treatment.

Number Of Recorded Dengue Cases Up 36% Over Last Year In Costa Rica

“A total of 8,480 people have been affected by dengue fever in Costa Rica” so far this year, representing an increase of 36 percent, or 2,230 more cases than during the same period last year, according to a Ministry of Health report, Xinhua News reports. “Among all the cases so far, only nine people were affected by hemorrhagic dengue fever, which is a more serious and sometimes mortal type of dengue, the report added,” the news service writes (9/17). Health authorities are urging people to eliminate possible sources of reproduction for mosquitoes, including disposing of old tires, according to a health ministry press release (9/11).

Growing Number Of Dengue Cases In India Increases Risk Of Disease Spreading Worldwide, Experts Warn

“An epidemic of dengue fever in India is fostering a growing sense of alarm even as government officials here have publicly refused to acknowledge the scope of a problem that experts say is threatening hundreds of millions of people, not just in India but around the world,” the New York Times reports. Dengue is endemic in half of the world’s countries and continuing to spread, experts say, according to the newspaper. In India’s capital, New Delhi, “where areas of standing water contribute to the epidemic’s growth, hospitals are overrun and feverish patients are sharing beds and languishing in hallways,” the newspaper writes. With officials citing 30,002 cases of dengue in India through October, “a 59 percent jump from the 18,860 recorded for all of 2011,” several experts say the true number of infections in the country is in the tens of millions, the New York Times notes.

Experimental Dengue Vaccine Protects Against 3 Of 4 Viral Strains, Study Results Show

“The world’s first vaccine against dengue fever, being developed by French drugmaker Sanofi SA, protected against three of the virus’s four strains in a keenly awaited clinical trial in Thailand,” the company announced on Wednesday, Reuters reports (Hirschler/Regan, 7/25). “The vaccine actually generated antibody responses against all four strains of the virus, but for some reason, one strain was still able to infect children who received the vaccine, the company said, and scientists are now trying to figure out why,” the Los Angeles Times’ “Science Now” blog reports, adding, “Meanwhile, a much larger trial involving 31,000 adults and children is now under way in 10 countries in Asia and Latin America” (Maugh, 7/26). Reuters notes, “Other drug companies are also working on dengue vaccines but Sanofi’s product is several years ahead” (7/25).

Also In Global Health News: Child Marriages; USAID In Afghanistan; Respiratory Diseases In El Salvador; Food Security Improving In Zimbabwe

Epoch Times Examines Child Marriage Hearing An Epoch Times article discusses a recent congressional hearing held by the Tom Lantos Human Rights Commission on child marriage. The piece includes comments by representatives from the Department of State, UNICEF, CARE and the International Center for Research on Women who “described the cycle of…

Government, Humanitarian Agencies Respond To Flooding In Philippines, Warn Of Disease Threat

“Philippine authorities are warning of the spread of diseases in cramped evacuation centers, days after flash floods hit the southern Philippines and claimed more than a thousand lives,” ABC/Asia Pacific News reports, noting that flooding also has affected the country’s northern provinces, displacing at least 50,000 people (Escalante, 12/20). Tropical Storm Washi “hit the main southern island of Mindanao over the weekend, bringing heavy rains, flash floods and overflowing rivers that swept whole coastal villages away,” forcing 44,000 people to evacuate the area, Agence France-Presse/Inquirer News writes (Celis, 12/21). Officials say hundreds of thousands of people are in need of humanitarian assistance, and the U.N. has stepped up its efforts in the area, the U.N. News Centre reports (12/20).

Recent Releases In Global Health

ASTMH Meeting Blog: The American Society of Tropical Medicine and Hygiene’s (ASTMH) “Annual Meeting Blog” has a number of posts from this week’s gathering, including: “The ethics of overseas clinical research”; an interview with John Cook, former ASTMH president; American attention to dengue fever; a profile of Michele Barry, senior…

Recent Releases In Global Health

Progress, Challenges In Curbing Neglected Tropical Diseases: “The effect of 30 years of neglect for these diseases in research and development of new diagnostics and drugs, and, crucially, in investing in training and education in vector-borne diseases, is evident. Most current drugs for neglected tropical diseases are old, and the…

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